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Understanding the connectivity and dynamics of avian influenza

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Why do virulent avian influenza viruses (AIVs) evolve in chickens but not in ducks?

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A puzzling question for years.

 

Colleagues at Erasmus showed species-specific selection upon co-infection with a mix of LP/HP AIVs. Ducks selected LPAIV. Chickens selected HPAIV.

https://doi.org/10.1371/journal.ppat.1011942 

Viral antigen expression in tissues of chickens and ducks

Viral antigen expression in tissues of chickens and ducks